From bioinformatic pattern analysis to evolutionary dynamics

نویسنده

  • Paulien Hogeweg
چکیده

Ribonucleïnezuur (RNA) vervult twee verschillende rollen binnen een cel. Enerzijds heeft het molecuul de functie om informatie op te slaan (net zoals desoxyribonucleïnezuur (DNA)), anderzijds dient het als katalysator (op een manier zoals ook eiwit deze rol vervult). Bovendien kan RNA optreden als katalysator voor zijn eigen reproductie. Het molecuul kan daarom worden beschouwd als een minimaal model om de afbeelding tussen een genoom en een organisme te bestuderen. Paulien Hogeweg, hoogleraar bio-informatica aan de Universiteit Utrecht, geeft een overzicht van de theoretische inzichten die in de laatste tien jaar over dit onderwerp zijn verkregen.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Bioinformatic and empirical analysis of a gene encoding serine/threonine protein kinase regulated in response to chemical and biological fertilizers in two maize (Zea mays L.) cultivars

Molecular structure of a gene, ZmSTPK1, encoding a serine/threonine protein kinase in maize was analyzed by bioinformatic tool and its expression pattern was studied under chemical biological fertilizers. Bioinformatic analysis cleared that ZmSTPK1 is located on chromosome 10, from position 141015332 to 141017582. The full genomic sequence of the gene is 2251 bp in length and includes 2 exons. ...

متن کامل

Evolutionary Analysis of Mammalian ACE2 and the Key Residues Involved in Binding to the Spike Protein Revealed Potential SARS-CoV-2 Hosts

Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spilled over to humans via wild mammals, entering the host cell using angiotensin-converting enzyme 2 (ACE2) as receptor through Spike (S) protein binding. While SARS-CoV-2 became fully adapted to humans and globally spread, some mammal species were infected back. The present study evaluated the potential risk of mammals...

متن کامل

A MODEL FOR EVOLUTIONARY DYNAMICS OF WORDS IN A LANGUAGE

Human language, over its evolutionary history, has emerged as one of the fundamental defining characteristic of the modern man. However, this milestone evolutionary process through natural selection has not left any ’linguistic fossils’ that may enable us to trace back the actual course of development of language and its establishment in human societies. Lacking analytical tools to fathom the cr...

متن کامل

Evolutionary Dynamics of a Locus of Fertility Restoration in Plants

In higher plants, hermaphrodites may genetically loose their male fertility through the cytoplasmic male sterility (CMS) system. In radish, a nuclear locus, denoted Rfo, has evolved that is able to counteract the effect of CMS and restore the fertility. This locus encodes three similar genes in tandem that belong to the pentatricopeptide repeat (PPR) family and each gene encloses a tandem repea...

متن کامل

Evaluation of the anti-Salmonella Aptamer using Bioinformatic Tools and ELAA Method

Background: Identifying and measuring food pathogens and environmental samples require accurate and high-sensitivity and specific methods. In addition, Salmonella is a zoonotic bacteria that can directly cause human disease. The aim of this work is to develop anti-Salmonella aptamer using bioinformatic tools and enzyme-linked aptamer assay (ELAA) for assessment of affinity and identifying Salmo...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2002